| dc.date.accessioned | 2023-09-05T14:44:23Z | |
| dc.date.issued | 2023 | |
| dc.identifier | doi:10.17170/kobra-202308318715 | |
| dc.identifier.uri | http://hdl.handle.net/123456789/15050 | |
| dc.language.iso | eng | eng |
| dc.rights | Urheberrechtlich geschützt | |
| dc.rights.uri | https://rightsstatements.org/page/InC/1.0/ | |
| dc.subject.ddc | 540 | |
| dc.subject.ddc | 570 | |
| dc.title | Biochemical Characterization of Microtubule-Associated Serine/Threonine Kinases | eng |
| dc.type | Dissertation | |
| dcterms.abstract | The association of human microtubule-associated serine/threonine (MAST) kinases with different diseases, such as neurodevelopmental disorders and cancer, leads to hight interest in understanding the function of these understudied kinases. This PhD thesis provides the first consolidated biochemical analysis of three different human MAST kinases (MAST1-3) and the Drosophila melanogaster homologue drop out protein (DOP). | eng |
| dcterms.abstract | Die Assoziation humaner Mikrotubuli-assoziierter Serin/Threonin (MAST) Kinasen mit Krankheiten, wie z. B. neurologischen Erkrankungen und Krebs, weckt das Interesse am Verständnis der Funktion dieser bisher wenig untersuchten Kinase. Diese Doktorarbeit liefert die erste konsolidierte biochemische Analyse drei verschiedener humaner MAST-Kinasen (MAST1-3) und des Drosophila melanogaster-Homologes Drop-out-Protein (DOP). | ger |
| dcterms.accessRights | open access | |
| dcterms.creator | Pautz, Sabine | |
| dcterms.dateAccepted | 2023-01-24 | |
| dcterms.extent | XII, 167 Seiten | |
| dc.contributor.corporatename | Kassel, Universität Kassel, Fachbereich Mathematik und Naturwissenschaften, Institut für Biologie | |
| dc.contributor.referee | Herberg, Friedrich Wilhelm (Prof. Dr.) | |
| dc.contributor.referee | Müller, Arno (Prof. Dr.) | |
| dc.contributor.referee | Schaffrath, Raffael (Prof. Dr.) | |
| dc.contributor.referee | Stengl, Monika (Prof. Dr.) | |
| dc.subject.swd | Kinasen | ger |
| dc.subject.swd | Protein-Serin-Threonin-Kinasen | ger |
| dc.subject.swd | Biochemische Analyse | ger |
| dc.subject.swd | Zellwachstum | ger |
| dc.subject.swd | MAPs | ger |
| dc.subject.swd | Mutation | ger |
| dc.subject.swd | Biochemische Eigenschaft | ger |
| dc.type.version | publishedVersion | |
| ubks.embargo.terms | 2024-01-24 | ger |
| ubks.embargo.end | 2024-01-24 | |
| kup.iskup | false | |
| ubks.epflicht | true | |
