Now showing items 21-30 of 763
tRNA anticodon loop modifications ensure protein homeostasis and cell morphogenesis in yeast
Using budding yeast, we investigated a negative interaction network among genes for tRNA modifications previously implicated in anticodon-codon interaction: 5-methoxy-carbonyl-methyl-2-thio-uridine (mcm5s2U34: ELP3, URM1), pseudouridine (Ψ38/39: DEG1) and cyclic N6-threonyl-carbamoyl-adenosine (ct6A37: TCD1). In line with functional cross talk between these modifications, we find that combined removal of either ct6A37 or Ψ38/39 and mcm5U34 or s2U34 results in morphologically altered cells with synthetic growth defects. ...
Optimal control theory for a unitary operation under dissipative evolution
We show that optimizing a quantum gate for an open quantum system requires the time evolution of only three states irrespective of the dimension of Hilbert space. This represents a significant reduction in computational resources compared to the complete basis of Liouville space that is commonly believed necessary for this task. The reduction is based on two observations: the target is not a general dynamical map but a unitary operation; and the time evolution of two properly chosen states is sufficient to ...
High-precision force sensing using a single trapped ion
We introduce quantum sensing schemes for measuring very weak forces with a single trapped ion. They use the spin-motional coupling induced by the laser-ion interaction to transfer the relevant force information to the spin-degree of freedom. Therefore, the force estimation is carried out simply by observing the Ramsey-type oscillations of the ion spin states. Three quantum probes are considered, which are represented by systems obeying the Jaynes-Cummings, quantum Rabi (in 1D) and Jahn-Teller (in 2D) models. By using ...
Skriptum zur Linearen Algebra und Analytischen Geometrie
Vorlesungsskript zur Vorlesung „Lineare Algebra und Analytische Geometrie“ an der Universität Kassel im Sommersemester 2020. Es handelt sich um die Druckversion.
The Impact of Visualizing Nested Sets. An Empirical Study on Tree Diagrams and Unit Squares
It is an ongoing debate, what properties of visualizations increase people’s performance when solving Bayesian reasoning tasks. In the discussion of the properties of two visualizations, i.e., the tree diagram and the unit square, we emphasize how both visualizations make relevant subset relations transparent. Actually, the unit square with natural frequencies reveals the subset relation that is essential for the Bayes’ rule in a numerical and geometrical way whereas the tree diagram with natural frequencies does it ...
No Evidence for Ionotropic Pheromone Transduction in the Hawkmoth Manduca sexta
Insect odorant receptors (ORs) are 7-transmembrane receptors with inverse membrane topology. They associate with the conserved ion channel Orco. As chaperon, Orco maintains ORs in cilia and, as pacemaker channel, Orco controls spontaneous activity in olfactory receptor neurons. Odorant binding to ORs opens OR-Orco receptor ion channel complexes in heterologous expression systems. It is unknown, whether this also occurs in vivo. As an alternative to this ionotropic transduction, experimental evidence is accumulating ...
Diversity of aphyllophoroid fungi from taxonomical and biogeographical perspectives
Comprehensive knowledge of biodiversity is a prerequisite for its long-term conservation and sustainable use. Fungi play crucial roles in ecosystems and are among the species-richest organism groups on Earth. However, all aspects of their diversity remain underexplored. In this study, we aimed to fill the gaps in occurrence data and taxonomy as well as in understanding spatial diversity patterns of aphyllophoroid fungi (non-gilled macroscopic Basidiomycota). We digitized and made openly accessible 4,041 records of ...
Assessing segmental versus non-segmental features in the ventral nervous system of onychophorans (velvet worms)
Background: Due to their phylogenetic position as one of the closest arthropod relatives, studies of the organisation of the nervous system in onychophorans play a key role for understanding the evolution of body segmentation in arthropods. Previous studies revealed that, in contrast to the arthropods, segmentally repeated ganglia are not present within the onychophoran ventral nerve cords, suggesting that segmentation is either reduced or might be incomplete in the onychophoran ventral nervous system. Results: ...
InP - based quantum dots for telecom wavelengths ranges
Long-distance quantum communication applications require sources of single photons, emitting at telecom wavelengths (around 1550 nm) with minimum attenu-ation losses of silica fiber. Semiconductor self-assembled InAs/InP-based quantum dots (QDs) are possible candidates to reach this spectral region. One of the challenges on the way is a QD asymmetry, which limits the fidelity of entangled photons. Therefore, morphological and optical properties of QDs should be improved in order to achieve the necessary quality and ...
Role of neurotransmitter GABA in the brain of the Madeira cockroach Rhyparobia maderae with focus on the circadian system
All living things are subject to biological rhythms. Circadian rhythms are generated by internal clocks which influence many biochemical and physiological processes, as well as various behaviors of an organism. These oscillators are synchronized by external "Zeitgeber" signals such as light-dark changes, temperature changes, as well as social contacts. Different studies identified the accessory medulla (AME), small neuropil at the ventromedian edge of the medulla, as the circadian pacemaker center of the cockroach ...