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Dissertation
The anatomy of velvet worms (Onychophora) as revealed by a multimethodological approach and three-dimensional reconstructions
(2024)
Onychophorans, or velvet worms, comprise a small group of worm-like, multi-legged terrestrial invertebrates. Since their discovery in 1826, these organisms have been investigated from different perspectives, particularly in the field of morphology—a discipline that provides the basis for functional and evolutionary inferences. Onychophorans are currently classified within Ecdysozoa (moulting animals) and form together with Tardigrada (water bears) and Arthropoda a clade named Panarthropoda. Therefore, onychophorans ...
Dissertation
Molecular mechanisms controlling the precision of chemokine guided cell migration
(2007-06-21)
By the end of the first day of embryonic development, zebrafish primordial germ cells (PGCs) arrive at the site where the gonad develops. In our study we investigated the mechanisms controlling the precision of primordial germ cell arrival at their target.
We found that in contrast with our expectations which were based on findings in Drosophila and mouse, the endoderm does not constitute a preferred migration substrate for the PGCs. Rather, endoderm derivatives are important for later stages of organogenesis keeping ...