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Dissertation
Finite Element Simulations for the Design of Therapeutic Approaches for Retinal Diseases
(2022)
The retinal disease age-related macular degeneration is the most common cause of vision loss in industrialized countries. In this thesis, motivated by the drug (antibody) treatment of this disease, we designed long-term three dimensional Finite Element simulations of the drug distribution in the healthy human eye. The underlying model consists of a time-dependent convection-diffusion equation coupled to a stationary Darcy equation describing the flow of the aqueous humor through the vitreous medium. We replaced the ...
Dissertation
Positive und konservative Verfahren höherer Ordnung
(2010-03-17)
In der Anwendung treten häufig Differentialgleichungssysteme auf, deren Komponenten über das Lösen mit einer vorgegeben Genauigkeit hinaus Anforderungen an die, zur Näherung verwendeten, numerischen Verfahren stellen. Die Arbeit widmet sich hierbei den beiden Forderungen
1. Erhaltung der Positivität aller positiven Größen (z.B. Massen, Konzentrationen, Energie) und
2. Erhaltung der Masse in abgeschlossenen Systemen.
Ausgehend von einem komplexen ökologischen 2D Modell zur Beschreibung von Algendynamiken in flachen ...
Dissertation
A Unifying Theory for Runge-Kutta-like Time Integrators: Convergence and Stability
(2024)
The work deals with two major topics concerning the numerical analysis of Runge-Kutta-like (RK-like) methods, namely their stability and order of convergence. RK-like methods differ from additive RK methods in that their coefficients are allowed to depend on the solution and the step size. As a result of this, we also refer to them as non-standard additive RK (NSARK) methods. We motivate and introduce modified Patankar (MP) schemes as a subclass of NSARK methods and emphasize their importance. The first major part ...