Search
Now showing items 21-26 of 26
Aufsatz
![Open Access](/themes/Mirage2/images/Open_Access_logo_PLoS_transparent.svg)
A multiscale approach reveals elaborate circulatory system and intermittent heartbeat in velvet worms (Onychophora)
(2023-04-28)
An antagonistic hemolymph-muscular system is essential for soft-bodied invertebrates. Many ecdysozoans (molting animals) possess neither a heart nor a vascular or circulatory system, whereas most arthropods exhibit a well-developed circulatory system. How did this system evolve and how was it subsequently modified in panarthropod lineages? As the closest relatives of arthropods and tardigrades, onychophorans (velvet worms) represent a key group for addressing this question. We therefore analyzed the entire circulatory ...
Aufsatz
![Open Access](/themes/Mirage2/images/Open_Access_logo_PLoS_transparent.svg)
An updated world checklist of velvet worms (Onychophora) with notes on nomenclature and status of names
(2023-11-16)
More than a decade has passed since the publication of the only world checklist available for Onychophora. During this period, numerous nomenclatural acts and taxonomic changes have been suggested within the group and a wealth of novel data has been published on many taxa. Herein, the up-to-date taxonomic scenario within Onychophora is presented, with appraisal of name status. This checklist covers both extant (Peripatidae and Peripatopsidae) and fossil taxa, and each species is accompanied by information on synonyms, ...
Aufsatz
![Open Access](/themes/Mirage2/images/Open_Access_logo_PLoS_transparent.svg)
Soil respiration under different N fertilization and irrigation regimes in Bengaluru, S-India
(2023-09-15)
Rapid urbanization in many countries of the Global South has led to intensification of urban and peri-urban agriculture (UPA) whose effects on the soils’ physical, chemical, and microbial properties have been hardly studied. We therefore investigated the effects of different intensity levels, exemplified by three rates of mineral nitrogen (N) addition and irrigation on CO₂ emissions in typical crops during the wet (Kharif) and dry (Rabi) season on a Nitisol in Bengaluru, S-India. Respiration data were collected from ...
Aufsatz
![Open Access](/themes/Mirage2/images/Open_Access_logo_PLoS_transparent.svg)
DPH1 Gene Mutations Identify a Candidate SAM Pocket in Radical Enzyme Dph1 Dph2 for Diphthamide Synthesis on EF2
(2023-11-16)
In eukaryotes, the Dph1•Dph2 dimer is a non-canonical radical SAM enzyme. Using iron-sulfur (FeS) clusters, it cleaves the cosubstrate S-adenosyl-methionine (SAM) to form a 3-amino-3-carboxy-propyl (ACP) radical for the synthesis of diphthamide. The latter decorates a histidine residue on elongation factor 2 (EF2) conserved from archaea to yeast and humans and is important for accurate mRNA translation and protein synthesis. Guided by evidence from archaeal orthologues, we searched for a putative SAM-binding pocket ...
Aufsatz
![Open Access](/themes/Mirage2/images/Open_Access_logo_PLoS_transparent.svg)
Yeast gene KTI13 (alias DPH8) operates in the initiation step of diphthamide synthesis on elongation factor 2
(2023-08-08)
In yeast, Elongator-dependent tRNA modifications are regulated by the Kti11•Kti13 dimer and hijacked for cell killing by zymocin, a tRNase ribotoxin. Kti11 (alias Dph3) also controls modification of elongation factor 2 (EF2) with diphthamide, the target for lethal ADP-ribosylation by diphtheria toxin (DT). Diphthamide formation on EF2 involves four biosynthetic steps encoded by the DPH1-DPH7 network and an ill-defined KTI13 function. On further examining the latter gene in yeast, we found that kti13Δ null-mutants ...
Aufsatz
![Open Access](/themes/Mirage2/images/Open_Access_logo_PLoS_transparent.svg)
Anthropogenic and natural disturbances increase local genetic diversity in an early spring geophyte (Ficaria verna Huds)
(2023-12-26)
The tetraploid Ficaria verna is a common spring geophyte in central Europe and is considered invasive in the USA and Canada. It is considered an almost seed-sterile taxon, relying on vegetative reproduction by underground tubers and aerial bulbils. Recent studies have revealed high levels of population genetic diversity in F. verna, raising the question of how genetic diversity is maintained and which factors may be responsible for the observed patterns. Polymorphic nuclear microsatellite markers were established to ...