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Dissertation
Investigation of the functional synergy and involvement of different tRNA modifications in translational control
(2020-07-02)
Transfer RNAs are essential adapter molecules employed in the translational process and are highly modified all over their structure. Specific modification of the four canonical ribonucleotides (A, U, C, G) is accomplished by various proteins and/or protein complexes, ranging from simple isomerisations (e.g. Ψ) and methylations (e.g. m5C) up to complex chemical structures (e.g. mcm5s2U, ct6A). The functions of tRNA modifications are linked to the specific position and may influence translation by supporting the native ...
Dissertation
Simulation, Validierung und Optimierung eines innovativen Kühlsystems bestehend aus PCM-Kühldecken und PINC-Anlage
(2020)
Das Integrieren von passiver infrarot Nachtkühlung (PINC) als volatile erneuerbare Energiequelle in wassergeführte Bürokühlsysteme durch Anwendung von deckenintegrierten aktiv regenerierbaren Phasenwechselmaterialien (PCM-Kühldecken) als dezentraler Kältespeicher im Raum zur Lastenverschiebung stellt ein innovatives Low-Ex Kühlsystem dar, das zwei Hauptprobleme aufweist. Diese Probleme sind einerseits die dynamische Wechselwirkung zwischen Erzeugung und Speicherung wegen der volatilen Kältequelle und der schwankenden ...
Dissertation
Internal Interruptions at Work
(2020)
This dissertation investigates internal interruptions at work, one of the main drivers of multitasking behaviour. The four empirical studies cumulated in this dissertation examine the preconditions to internal interruptions at work, the reasons behind why individuals interrupt themselves, the strategic advantage of internal interruptions, and impact of internal interruptions on performance. The main goals of this dissertation are to uncover the underlying processes of internal interruptions and observe it in real ...
Dissertation
The tRNA binding protein Kti12 and its role in the regulation of Elongator complex
(2020-06-08)
[Summary] Kti12 is a conserved eukaryotic protein showing sequence homology to O-phosphoseryltRNA kinase (Pstk), which is required for the synthesis of selenocysteine tRNA. Saccharomyces cerevisiae Kti12 was originally discovered in a genetic screening for resistance against zymocin, a protein toxin produced by Kluyveromyces lactis. The cytotoxicity of zymocin lies in its anticodon nuclease activity, causing tRNA depletion and cell death in sensitive yeast cells. It recognizes and cleaves a particular wobble uridine ...
Dissertation
Behaviour Study of Grouted Connection for Offshore Wind Turbine Structures with Brittle Cement Based Grouts
(2020)
Researches show that the energy demand in the world is significantly increasing and climate change becomes a problematic issue, therefore, the interest in renewable energy is growing extremely fast. Offshore wind energy is one of the most effective renewable sources in Europe and other places in the world. One of the most important parts in the offshore foundation is the grouted connection as it is the first element to be designed in the design of the foundation structure of an offshore wind turbine because the ...
Dissertation
Process optimisation and development of non-invasive monitoring approaches for the drying of apples
(2020)
Drying is of great importance particularly in the field of preserving agricultural products. It plays a very critical role by delivering nutrient rich products with a long shelf-life as well as help to combat food loss. Drying processing techniques have changed and improved significantly over time, helping to ensure food abundance in both aesthetical and nutritional regards. Convective hot air drying is one of the most common technique practiced by 85 % of industries. It can be easily applied in the remote areas of ...
Dissertation
Crowd-Based Entrepreneurship
(2020)
The aim of this dissertation is to explore the innovation potential of crowdsourcing for entrepreneurship. The main focus is to discover how crowd-based infrastructures (i. e., crowdsourcing platforms and crowdfunding platforms) can support entrepreneurs in their innovation activities and how this new paradigm can be used to generate value for customers as well as actors of entrepreneurial ecosystems. The results of the dissertation show that crowdsourcing offers numerous opportunities to support entrepreneurs in ...
Dissertation
Food commercialization, hidden hunger and malnutrition: A study of food and nutrition security, focusing on the marginalized society in Sri Lanka
(2020-09)
From 2016 to 2019, a collaborative research project between the Rajarata University of Sri Lanka and the Department of Organic Food Quality and Food Culture, University of Kassel, Germany, was carried out to investigate the food commercialization, hidden hunger, and malnutrition in marginalized societies in Sri Lanka.
Consuming a healthy diet, maintaining good health, and chronic diseases is a challenge for those struggling with poverty and food insecurity for various reasons in Sri Lanka, including limited financial ...
Dissertation
Assessment of genetic diversity in local breeds
(2020-06)
The present study aimed at assessing genetic diversity in selected local livestock breeds in Northern Germany, and furthermore, examining some of the indices used in describing diversity in populations. The study begun with an assessment of genetic diversity in the German Angler (RVA) and Red-and-white dual-purpose (RDN) cattle breeds. Analyses of the RVA and RDN pedigrees, consisting of 93,078 and 184,358 records, respectively, revealed a number of Red Holstein (RH) sires that were influential in these breeds. Even ...
Dissertation
Energy Budget- and Temperature Index- based Calculations of Seasonal Mass Balances and Discharge in the Tropical Glacier Artesonraju and Artesoncocha Basin in the Cordillera Blanca,
Peru
(2020)
The core of the present Doctoral study deals with glacier simulations for calculating mass balance and discharge in the Artesonraju glacier and Artesoncocha basin, in the Cordillera Blanca (CB), Peru. For this purpose, two different models are used. One is an energy-model (EBM) which is physically based and uses energy fluxes measurements on the glaciers, whereas the other one is a temperature index model (TIM) which is empirical and uses mainly temperature and precipitation as its main input data.
An analysis of ...