View/ Open
Date
2023-08-18xmlui.dri2xhtml.METS-1.0.item-supplement
doi:10.48662/daks-35Metadata
Show full item record
Aufsatz
Influence of Ethylene Oxide and Gamma Irradiation Sterilization Processes on the Properties of Poly-L-Lactic-Acid (PLLA) Materials
Abstract
In order to encourage the substitution of petrochemical polymers in medical technology with sustainable, bio-based materials, there is an urgent need for further investigations, especially data regarding their sterility performance. Within the scope of the investigations, selected material properties of poly-L-lactic-acid (PLLA), a specific type of poly(lactic-acid) (PLA), were analyzed before and after sterilization (using ethylene oxide or gamma irradiation) in order to investigate deviations in its chemical structure, wettability, optical, and mechanical properties. In particular, parameters such as molecular weight, complex viscosity, tensile strength, water contact angle, and color were discussed. Sterilization temperatures close to the glass transition of PLA, high humidity, and interactions with the ethylene oxide molecules have resulted in an increase in crystallinity, a decrease in elongation at break, and in some cases, a variation in wettability. As a consequence of exposure to high-energy radiation, the material’s toughness is reduced due to chain scission, which is manifested through a decrease in molecular weight, an increase in crystallinity, and a partial change in surface energy. For the selected PLLA-materials (Luminy® L130, NP HT 202, and NP HT 203), ethylene oxide sterilization resulted in a comparatively minor variation in the characteristics behavior, and was chosen as the preferred method.
Citation
In: Polymers Volume 15 / Issue 16 (2023-08-18) eissn:2073-4360Sponsorship
Gefördert durch den Publikationsfonds der Universität KasselCitation
@article{doi:10.17170/kobra-202310058826,
author={Krug, Natalie and Zarges, Jan-Christoph and Heim, Hans-Peter},
title={Influence of Ethylene Oxide and Gamma Irradiation Sterilization Processes on the Properties of Poly-L-Lactic-Acid (PLLA) Materials},
journal={Polymers},
year={2023}
}
0500 Oax 0501 Text $btxt$2rdacontent 0502 Computermedien $bc$2rdacarrier 1100 2023$n2023 1500 1/eng 2050 ##0##http://hdl.handle.net/123456789/15102 3000 Krug, Natalie 3010 Zarges, Jan-Christoph 3010 Heim, Hans-Peter 4000 Influence of Ethylene Oxide and Gamma Irradiation Sterilization Processes on the Properties of Poly-L-Lactic-Acid (PLLA) Materials / Krug, Natalie 4030 4060 Online-Ressource 4085 ##0##=u http://nbn-resolving.de/http://hdl.handle.net/123456789/15102=x R 4204 \$dAufsatz 4170 5550 {{Medizinisches Gerät}} 5550 {{Biopolymere}} 5550 {{Ethylenoxid}} 5550 {{Gammabestrahlung}} 7136 ##0##http://hdl.handle.net/123456789/15102
2023-10-06T10:52:13Z 2023-10-06T10:52:13Z 2023-08-18 doi:10.17170/kobra-202310058826 http://hdl.handle.net/123456789/15102 Gefördert durch den Publikationsfonds der Universität Kassel eng Namensnennung 4.0 International http://creativecommons.org/licenses/by/4.0/ bioplastics poly-L-lactic-acid (PLLA) sterilization gamma irradiation ethylene oxide single-use products medical devices 530 540 Influence of Ethylene Oxide and Gamma Irradiation Sterilization Processes on the Properties of Poly-L-Lactic-Acid (PLLA) Materials Aufsatz In order to encourage the substitution of petrochemical polymers in medical technology with sustainable, bio-based materials, there is an urgent need for further investigations, especially data regarding their sterility performance. Within the scope of the investigations, selected material properties of poly-L-lactic-acid (PLLA), a specific type of poly(lactic-acid) (PLA), were analyzed before and after sterilization (using ethylene oxide or gamma irradiation) in order to investigate deviations in its chemical structure, wettability, optical, and mechanical properties. In particular, parameters such as molecular weight, complex viscosity, tensile strength, water contact angle, and color were discussed. Sterilization temperatures close to the glass transition of PLA, high humidity, and interactions with the ethylene oxide molecules have resulted in an increase in crystallinity, a decrease in elongation at break, and in some cases, a variation in wettability. As a consequence of exposure to high-energy radiation, the material’s toughness is reduced due to chain scission, which is manifested through a decrease in molecular weight, an increase in crystallinity, and a partial change in surface energy. For the selected PLLA-materials (Luminy® L130, NP HT 202, and NP HT 203), ethylene oxide sterilization resulted in a comparatively minor variation in the characteristics behavior, and was chosen as the preferred method. open access Krug, Natalie Zarges, Jan-Christoph Heim, Hans-Peter doi:10.3390/polym15163461 doi:10.48662/daks-35 Medizinisches Gerät Biopolymere Ethylenoxid Gammabestrahlung publishedVersion eissn:2073-4360 Issue 16 Polymers Volume 15 false 3461
The following license files are associated with this item: