Datum
2021-05-13Autor
Milan, Eduardo P.Rodrigues, Murilo Álison VigilatoMartins, Virginia da Conceição AmaroPlepis, Ana Maria de GuzziFuhrmann-Lieker, ThomasHorn, Marilia MartaSchlagwort
540 Chemie 570 Biowissenschaften, Biologie FischeHautKollagenMangostanePhosphorylierungMineralisationMetadata
Zur Langanzeige
Aufsatz
Mineralization of Phosphorylated Fish Skin Collagen/Mangosteen Scaffolds as Potential Materials for Bone Tissue Regeneration
Zusammenfassung
In this study, a potential hard tissue substitute was mimicked using collagen/mangosteen porous scaffolds. Collagen was extracted from Tilapia fish skin and mangosteen from the waste peel of the respective fruit. Sodium trimetaphosphate was used for the phosphorylation of these scaffolds to improve the nucleation sites for the mineralization process. Phosphate groups were incorporated in the collagen structure as confirmed by their attenuated total reflection Fourier transform infrared (ATR-FTIR) bands. The phosphorylation and mangosteen addition increased the thermal stability of the collagen triple helix structure, as demonstrated by differential scanning calorimetry (DSC) and thermogravimetry (TGA) characterizations. Mineralization was successfully achieved, and the presence of calcium phosphate was visualized by scanning electron microscopy (SEM). Nevertheless, the porous structure was maintained, which is an essential characteristic for the desired application. The deposited mineral was amorphous calcium phosphate, as confirmed by energy dispersive X-ray spectroscopy (EDX) results.
Zitierform
In: Molecules Volume 26 / Issue 10 (2021-05-13) eissn:1420-3049Förderhinweis
Gefördert durch den Publikationsfonds der Universität KasselZitieren
@article{doi:10.17170/kobra-202106244160,
author={Milan, Eduardo P. and Rodrigues, Murilo Álison Vigilato and Martins, Virginia da Conceição Amaro and Plepis, Ana Maria de Guzzi and Fuhrmann-Lieker, Thomas and Horn, Marilia Marta},
title={Mineralization of Phosphorylated Fish Skin Collagen/Mangosteen Scaffolds as Potential Materials for Bone Tissue Regeneration},
journal={Molecules},
year={2021}
}
0500 Oax 0501 Text $btxt$2rdacontent 0502 Computermedien $bc$2rdacarrier 1100 2021$n2021 1500 1/eng 2050 ##0##http://hdl.handle.net/123456789/12953 3000 Milan, Eduardo P. 3010 Rodrigues, Murilo Álison Vigilato 3010 Martins, Virginia da Conceição Amaro 3010 Plepis, Ana Maria de Guzzi 3010 Fuhrmann-Lieker, Thomas 3010 Horn, Marilia Marta 4000 Mineralization of Phosphorylated Fish Skin Collagen/Mangosteen Scaffolds as Potential Materials for Bone Tissue Regeneration / Milan, Eduardo P. 4030 4060 Online-Ressource 4085 ##0##=u http://nbn-resolving.de/http://hdl.handle.net/123456789/12953=x R 4204 \$dAufsatz 4170 5550 {{Fische}} 5550 {{Haut}} 5550 {{Kollagen}} 5550 {{Mangostane}} 5550 {{Phosphorylierung}} 5550 {{Mineralisation}} 7136 ##0##http://hdl.handle.net/123456789/12953
2021-06-30T11:01:48Z 2021-06-30T11:01:48Z 2021-05-13 doi:10.17170/kobra-202106244160 http://hdl.handle.net/123456789/12953 Gefördert durch den Publikationsfonds der Universität Kassel eng Namensnennung 4.0 International http://creativecommons.org/licenses/by/4.0/ fish skin collagen mangosteen phosphorylation mineralization 540 570 Mineralization of Phosphorylated Fish Skin Collagen/Mangosteen Scaffolds as Potential Materials for Bone Tissue Regeneration Aufsatz In this study, a potential hard tissue substitute was mimicked using collagen/mangosteen porous scaffolds. Collagen was extracted from Tilapia fish skin and mangosteen from the waste peel of the respective fruit. Sodium trimetaphosphate was used for the phosphorylation of these scaffolds to improve the nucleation sites for the mineralization process. Phosphate groups were incorporated in the collagen structure as confirmed by their attenuated total reflection Fourier transform infrared (ATR-FTIR) bands. The phosphorylation and mangosteen addition increased the thermal stability of the collagen triple helix structure, as demonstrated by differential scanning calorimetry (DSC) and thermogravimetry (TGA) characterizations. Mineralization was successfully achieved, and the presence of calcium phosphate was visualized by scanning electron microscopy (SEM). Nevertheless, the porous structure was maintained, which is an essential characteristic for the desired application. The deposited mineral was amorphous calcium phosphate, as confirmed by energy dispersive X-ray spectroscopy (EDX) results. open access Milan, Eduardo P. Rodrigues, Murilo Álison Vigilato Martins, Virginia da Conceição Amaro Plepis, Ana Maria de Guzzi Fuhrmann-Lieker, Thomas Horn, Marilia Marta doi:10.3390/molecules26102899 Fische Haut Kollagen Mangostane Phosphorylierung Mineralisation publishedVersion eissn:1420-3049 Issue 10 Molecules Volume 26 false 2899
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