Show simple item record

Influence of Ethylene Oxide and Gamma Irradiation Sterilization Processes on the Properties of Poly-L-Lactic-Acid (PLLA) Materials

dc.date.accessioned2023-10-06T10:52:13Z
dc.date.available2023-10-06T10:52:13Z
dc.date.issued2023-08-18
dc.identifierdoi:10.17170/kobra-202310058826
dc.identifier.urihttp://hdl.handle.net/123456789/15102
dc.description.sponsorshipGefördert durch den Publikationsfonds der Universität Kassel
dc.language.isoeng
dc.rightsNamensnennung 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectbioplasticseng
dc.subjectpoly-L-lactic-acid (PLLA)eng
dc.subjectsterilizationeng
dc.subjectgamma irradiationeng
dc.subjectethylene oxideeng
dc.subjectsingle-use productseng
dc.subjectmedical deviceseng
dc.subject.ddc530
dc.subject.ddc540
dc.titleInfluence of Ethylene Oxide and Gamma Irradiation Sterilization Processes on the Properties of Poly-L-Lactic-Acid (PLLA) Materialseng
dc.typeAufsatz
dcterms.abstractIn order to encourage the substitution of petrochemical polymers in medical technology with sustainable, bio-based materials, there is an urgent need for further investigations, especially data regarding their sterility performance. Within the scope of the investigations, selected material properties of poly-L-lactic-acid (PLLA), a specific type of poly(lactic-acid) (PLA), were analyzed before and after sterilization (using ethylene oxide or gamma irradiation) in order to investigate deviations in its chemical structure, wettability, optical, and mechanical properties. In particular, parameters such as molecular weight, complex viscosity, tensile strength, water contact angle, and color were discussed. Sterilization temperatures close to the glass transition of PLA, high humidity, and interactions with the ethylene oxide molecules have resulted in an increase in crystallinity, a decrease in elongation at break, and in some cases, a variation in wettability. As a consequence of exposure to high-energy radiation, the material’s toughness is reduced due to chain scission, which is manifested through a decrease in molecular weight, an increase in crystallinity, and a partial change in surface energy. For the selected PLLA-materials (Luminy® L130, NP HT 202, and NP HT 203), ethylene oxide sterilization resulted in a comparatively minor variation in the characteristics behavior, and was chosen as the preferred method.eng
dcterms.accessRightsopen access
dcterms.creatorKrug, Natalie
dcterms.creatorZarges, Jan-Christoph
dcterms.creatorHeim, Hans-Peter
dc.relation.doidoi:10.3390/polym15163461
dc.relation.issupplementedbydoi:10.48662/daks-35
dc.subject.swdMedizinisches Gerätger
dc.subject.swdBiopolymereger
dc.subject.swdEthylenoxidger
dc.subject.swdGammabestrahlungger
dc.type.versionpublishedVersion
dcterms.source.identifiereissn:2073-4360
dcterms.source.issueIssue 16
dcterms.source.journalPolymerseng
dcterms.source.volumeVolume 15
kup.iskupfalse
dcterms.source.articlenumber3461


Files in this item

Thumbnail
Name:
license_rdf
Size:
908bytes
Format:
application/rdf+xml
View/Open
Thumbnail
Name:
polymers_15_03461_v4.pdf
Size:
3.826Mb
Format:
PDF
View/Open

This item appears in the following Collection(s)

Show simple item record

Namensnennung 4.0 International
Except where otherwise noted, this item's license is described as Namensnennung 4.0 International