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Dissertation
Synthese und Reaktivität eines cyclischen (Alkyl)(amino)carbens mit 1,1'-Ferrocenylen-Rückgrat
(2023-01)
Ziel der vorliegenden Arbeit war es, cyclische (Alkyl)(amino)carbene mit einem 1,1‘ Ferrocenylen-Rückgrat (fcCAACs) darzustellen und zu charakterisieren und somit eine Kombination aus bekanntermaßen jeweils höchst ambiphilen CAACs und N-heterocyclischen Carbenen mit 1,1‘-Ferrocenylen-Rückgrat (fcNHCs) zu schaffen. Durch das fc-Rückgrat sollten die Zielverbindungen eine im Vergleich zu bisher zugänglichen CAACs noch ausgeprägtere Ambiphilie besitzen und somit eine nochmals gesteigerte Reaktivität zeigen, insbesondere ...
Dissertation
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Fabrication and Investigation of Diamond Membranes for Photonic Nanostructures
(2023)
Due to its exceptional physical and chemical characteristics, diamond in a form of thin membranes is a particularly promising material for the fabrication of high-quality photonic devices. Especially for envisioned applications in quantum information technologies and communication, diamond gained, as a host material, an ever-increasing scientific interest based on remarkable properties of different color centers in its crystal lattice, e.g. nitrogen-vacancy centers, serving as single-photon emitters. As a high index ...
Dissertation
Analysis of a Coupled Fluid-Elastic Interaction Problem
(2023-01)
In this thesis, a non-linear system of partial differential equations is studied, describing the motions of an elastic structure which is immersed into an incompressible viscous fluid. The displacement of the elastic structure is modelled by a Lamé system and the fluid velocity as well as the fluid pressure are described by the Navier-Stokes equations. The structure and the fluid are coupled via two boundary conditions at the interface which correspond to continuity of velocities and forces. As the elasticity is ...
Dissertation
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Application of Temporal Airy Pulses for investigating the origin of Laser Induced Periodic Surface Structures and for developing new tools in cell surgery and malignant tissue identification
(2023)
In this thesis, ultrashort Temporal Airy Pulses are used to study Laser Induced Periodic Surface Structures (LIPSS) in Part I and to enable the photoinjection of fluorescent markers into single living cells in Part II, Chapter 8. In both cases, the laser pulse excites a dielectric material (fused silica and water) and the special spatio-temporal dynamics of the interaction of a Temporal Airy Pulse with the dielectric is exploited to extend the shape of the excited region along the axis of laser propagation. For the ...
Habilitation
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Computing Ground States for Fermi-Bose Mixtures through Efficient Numerical Methods
(2023-05)
In this work, we will first review the Quantum Mechanics theory to derive the main equations. Next, we will analyze these equations by Functional Analysis methods to find conditions for existence, uniqueness, multiplicity, and other properties as positivity. Next, we will review and develop some numerical methods for solving the nonlinear Schrödinger equation, its time version, generalizations with rotational terms, and systems of NLSE (NLSS). We notice that the main problem to run numerical methods is the memory ...
Dissertation
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Control of Open Quantum Systems: Examples & Methods for Non-Markovian Dynamics
(2023)
Usually open quantum systems are considered to be under the influence of noise and therefore faulty. On the other hand, a controlled system is regarded as something stable and predictable. It is often neglected, that the two aspects are very closely related. A perfectly isolated quantum system will not be subject to environmental influences, but this makes it also impossible to interact with it in any manner. Controlling and measuring such a system is impossible and therefore of no technical relevance. Every system ...
Dissertation
Biochemical Characterization of Microtubule-Associated Serine/Threonine Kinases
(2023)
The association of human microtubule-associated serine/threonine (MAST) kinases with different diseases, such as neurodevelopmental disorders and cancer, leads to hight interest in understanding the function of these understudied kinases. This PhD thesis provides the first consolidated biochemical analysis of three different human MAST kinases (MAST1-3) and the Drosophila melanogaster homologue drop out protein (DOP).
Dissertation
Functional Analysis of Src42A in embryonic epithelial morphogenesis of Drosophila melanogaster
(2023)
Src42A is one of the Src family kinases (SFKs) present in Drosophila melanogaster. In mammals there are 8 SFKs and so far, a loss of function analysis of SFKs were difficult to conduct due to their functional redundancy. In Drosophila, there are only two SFKs namely Src42A and Src64B, the former is essential for embryonic development and the latter is a non-essential gene. Since Src42A is supplied as a maternal component, the zygotic mutant were showing defects in later developmental stages, because the contribution ...