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Now showing items 61-70 of 258
Aufsatz
SSPIM: a beam shaping toolbox for structured selective plane illumination microscopy
(2018-07-03)
Selective plane illumination microscopy (SPIM) represents a preferred method in dynamic tissue imaging, because it combines high spatiotemporal resolution with low phototoxicity. The OpenSPIM system was developed to provide an accessible and flexible microscope set-up for non-specialist users. Here, we report Structured SPIM (SSPIM), which offers an open-source, user-friendly and compact toolbox for beam shaping to be applied within the OpenSPIM platform. SSPIM is able to generate digital patterns for a wide range ...
Aufsatz
Short-spored Subulicystidium (Trechisporales, Basidiomycota): high morphological diversity and only partly clear species boundaries
(2018-06-27)
Diversity of corticioid fungi (resupinate Basidiomycota), especially outside the northern temperate climatic zone, remains poorly explored. Furthermore, most of the known species are delimited by morphological concepts only and, not rarely, these concepts are too broad and need to be tested by molecular tools. For many decades, the delimitation of species in the genus Subulicystidium (Hydnodontaceae, Trechisporales) was a challenge for mycologists. The presence of numerous transitional forms as to basidiospore size ...
Aufsatz
S-Adenosyl-L-Homocysteine Hydrolase Inhibition by a Synthetic Nicotinamide Cofactor Biomimetic
(2018-03-21)
S-adenosyl-L-homocysteine (SAH) hydrolases (SAHases) are involved in the regulation of methylation reactions in many organisms and are thus crucial for numerous cellular functions. Consequently, their dysregulation is associated with severe health problems. The SAHase-catalyzed reaction is reversible and both directions depend on the redox activity of nicotinamide adenine dinucleotide (NAD+) as a cofactor. Therefore, nicotinamide cofactor biomimetics (NCB) are a promising tool to modulate SAHase activity. In the ...
Aufsatz
Water Quality in Surface Water: A Preliminary Assessment of Heavy Metal Contamination of the Mashavera River, Georgia
(2018-03-23)
Water quality contamination by heavy metal pollution has severe effects on public health. In the Mashavera River Basin, an important agricultural area for the national food system in Georgia (e.g., vegetable, dairy and wine production), water contamination has multiple influences on the regional and country-wide health. With new industrial activities in the region, sediment extraction, and discharge of untreated wastewater into the river, its tributaries and irrigation canals, a comprehensive study of water quality ...
Dissertation
Analysis and Projection of spatio-temporal Drought and Climate Change Impacts on Groundwater Resources and Surface-Groundwater Interactions for three Iranian Case Studies
(2018-08)
Der Klimawandel und deren Variabilität, wie z.B. die Dürre, wirken sich auf die Wasserressourcen und insbesondere auf die wertvolle Grundwasserressource aus, die im Iran mehr als 80% des Wasserbedarfs aller Bereiche (Landwirtschaft, Haushalt und Industrie) ausmacht. Es ist von größter Bedeutung, Anpassungsstrategien zur Bewältigung dieser Probleme zu finden, um ein nachhaltiges Wasserressourcenmanagement sicherzustellen. In dieser Hinsicht sind physikalisch basierte hydrologische Modelle gekoppelt mit Grundwassermodellen ...
Dissertation
Lösungen linearer Polynomgleichungen in Funktionenkörpern und Uniformisierbarkeit von t-Moduln
(2018)
Bei abelschen t-Moduln über Funktionenkörpern, denen der Ring F_q[t] zugrunde liegt, spielt die Frage der Uniformisierbarkeit eine wichtige Rolle. In dieser Arbeit werden t-Moduln betrachtet, die durch
t = τ^2 + A τ+ θ
gegeben sind, wobei τ den q-Frobenius-Endomorphismus bezeichnet, A eine (d x d)-Matrix mit d = 2 ist und θ eine Unbestimmte über F_q ist, die als Skalar (der t entspricht) im Funktionenkörper F_q(( 1/θ )) aufgefasst wird.
Nach einem Satz von Anderson aus der grundlegenden Arbeit “t-motives” (1986) ...
Aufsatz
Requirement of the Dynein-Adaptor Spindly for Mitotic and Post-Mitotic Functions in Drosophila
(2018-03-30)
Spindly was originally identified as a specific regulator of Dynein activity at the kinetochore. In early prometaphase, Spindly recruits the Dynein/Dynactin complex, promoting the establishment of stable kinetochore-microtubule interactions and progression into anaphase. While details of Spindly function in mitosis have been worked out in cultured human cells and in the C. elegans zygote, the function of Spindly within the context of an organism has not yet been addressed. Here, we present loss- and gain-of-function ...
Aufsatz
Exploring the Supply-Demand-Discrepancy of Sustainable Financial Products in Germany from a Financial Advisor’s Point of View
(2018-03-23)
Although retail investors’ interest in sustainable investment is constantly increasing, German credit unions and co-operative banks offer few sustainable financial products. The purpose of the study is to explore the current gap between supply and demand of sustainable financial investments in German retail banking from a financial advisor’s point of view. We use qualitative analysis of interviews with financial advisors based on a Grounded Theory approach with the aim to identify the key causation in the cause-effect ...
Aufsatz
Protein Phosphatase Sit4 Affects Lipid Droplet Synthesis and Soraphen A Resistance Independent of Its Role in Regulating Elongator Dependent tRNA Modification
(2018-07-11)
The protein phosphatase Sit4 has been shown to be required for lipogenesis and resistance against the acetyl-CoA carboxylase inhibitor soraphen A. Since Sit4 is also required for biosynthesis of Elongator dependent tRNA modifications such as 5-methoxycarbonylmethyluridine (mcm5U), we investigated the relevance of tRNA modifications in lipogenesis and soraphen A response. While sit4 and Elongator (elp3) mutants copy defects in mcm5U formation and stress sensitivity, they do not share soraphen A sensitivity and low ...
Aufsatz
Rainfall Prediction with AMSR–E Soil Moisture Products Using SM2RAIN and Nonlinear Autoregressive Networks with Exogenous Input (NARX) for Poorly Gauged Basins: Application to the Karkheh River Basin, Iran
(2018-07-23)
Accurate estimates of daily rainfall are essential for understanding and modeling the physical processes involved in the interaction between the land surface and the atmosphere. In this study, daily satellite soil moisture observations from the Advanced Microwave Scanning Radiometer–Earth Observing System (AMSR–E) generated by implementing the standard National Aeronautics and Space Administration (NASA) algorithm are employed for estimating rainfall, firstly, through the use of recently developed approach, SM2RAIN ...