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Aufsatz
S-Adenosyl-L-Homocysteine Hydrolase Inhibition by a Synthetic Nicotinamide Cofactor Biomimetic
(2018-03-21)
S-adenosyl-L-homocysteine (SAH) hydrolases (SAHases) are involved in the regulation of methylation reactions in many organisms and are thus crucial for numerous cellular functions. Consequently, their dysregulation is associated with severe health problems. The SAHase-catalyzed reaction is reversible and both directions depend on the redox activity of nicotinamide adenine dinucleotide (NAD+) as a cofactor. Therefore, nicotinamide cofactor biomimetics (NCB) are a promising tool to modulate SAHase activity. In the ...
Aufsatz
Metallated [3]Ferrocenophanes Containing P3M Bridges (M = Li, Na, K)
(2018-07-11)
Alkali-metal phosphanides can be embedded into a [3]ferrocenophane scaffold giving rise to bicyclic ferrocenophanes [MFe(C5H4PtBu)2P] (M = Li, Na, K). Coordination of the alkali-metal ions takes place via the terminal phosphorus atoms adopting a puckered P3M four-membered ring. All compounds were characterized via single-crystal X-ray diffraction and multinuclear NMR spectroscopy (1H, 31P, 7Li), whereas 13C NMR data could only be recorded for the Li derivative, owing to the limited solubility of its heavier congeners ...
Aufsatz
Synthesis and crystal structure of μ-[1,1′-di(mesitylphosphanido)ferrocene]bis[η5-cyclopentadienylnickel(II)] tetrahydrofurane solvate, C42H48FeNi2OP2
(2018-03-08)
C42H48FeNi2OP2, orthorhombic, Pbca (no. 61), a = 9.4551(4) Å, b = 19.7133(9) Å, c = 39.693(2) Å, V = 7398.4(6) Å3, Z = 8, Rgt(F) = 0.0598, wRref(F2) = 0.1481, T = 100(2) K.
Aufsatz
Characterization of polyamide 6.10 composites incorporated with microcrystalline cellulose fiber: Effects of fiber loading and impact modifier
(2018-08-14)
Microcrystalline cellulose (MCC) fiber‐reinforced polyamide 6.10 (PA) composites were prepared in the presence of an impact modifier (IM), exxelor VA1803 (VA), by melt compounding process. Fiber loading was considered from 20 to 30 wt.%, whereas IM was varied from 2.0 to 5.0 wt.%. Composites were characterized by tensile test, impact test, dynamic thermal mechanical analysis (DTMA), differential scanning calorimetry (DSC), thermogravimetric analysis (TGA), and X‐ray diffraction (XRD). Composites’ fractured surfaces ...