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Expression of NK genes that are not part of the NK cluster in the onychophoran Euperipatoides rowelli (Peripatopsidae)
(2019-04-15)
Background :
NK genes are a group of homeobox transcription factors that are involved in various molecular pathways across bilaterians. They are typically divided into two subgroups, the NK cluster (NKC) and NK-linked genes (NKL). While the NKC genes have been studied in various bilaterians, corresponding data of many NKL genes are missing to date. To further investigate the ancestral roles of NK family genes, we analyzed the expression patterns of NKL genes in the onychophoran Euperipatoides rowelli.
Results:
The ...
Aufsatz
X-ray imaging of a water bear offers a new look at tardigrade internal anatomy
(2019-05-11)
Background:
Tardigrades (water bears) are microscopic invertebrates of which the anatomy has been well studied using traditional techniques, but a comprehensive three-dimensional reconstruction has never been performed. In order to close this gap, we employed X-ray computed tomography (CT), a technique that is becoming increasingly popular in zoology for producing high-resolution, three-dimensional (3D) scans of whole specimens. While CT has long been used to scan larger samples, its use in some microscopic animals ...
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Investigation of dynamic quality changes and optimization of drying parameters of carrots (Daucus carota var. laguna)
(2019-11-29)
The effect of air temperature and sample thickness on the color changes and total carotenoids content of carrot slices was investigated. Temperature, exposure time, and moisture levels significantly affected the dynamic changes of total carotenoids and color. A slow and linear decrease in total carotenoids was observed at higher moisture content until reaching an inflection point at around 0.45 gw/gdm for all temperatures studied. Thereafter, the retention in total carotenoids decreased rapidly. The highest retention ...
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Requirement of the Dynein-Adaptor Spindly for Mitotic and Post-Mitotic Functions in Drosophila
(2018-03-30)
Spindly was originally identified as a specific regulator of Dynein activity at the kinetochore. In early prometaphase, Spindly recruits the Dynein/Dynactin complex, promoting the establishment of stable kinetochore-microtubule interactions and progression into anaphase. While details of Spindly function in mitosis have been worked out in cultured human cells and in the C. elegans zygote, the function of Spindly within the context of an organism has not yet been addressed. Here, we present loss- and gain-of-function ...
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Halloween genes in panarthropods and the evolution of the early moulting pathway in Ecdysozoa
(2018-09-01)
Moulting is a characteristic feature of Ecdysozoa—the clade of moulting animals that includes the hyperdiverse arthropods and less speciose groups, such as onychophorans, tardigrades and nematodes. Moulting has been best analysed in arthropods, specifically in insects and crustaceans, in which a complex neuroendocrine system acts at the genomic level and initiates the transcription of genes responsible for moulting. The key moulting hormones, ecdysone and 20-hydroxyecdysone, are subsequently synthesized from cholesterol ...
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Exploring the Supply-Demand-Discrepancy of Sustainable Financial Products in Germany from a Financial Advisor’s Point of View
(2018-03-23)
Although retail investors’ interest in sustainable investment is constantly increasing, German credit unions and co-operative banks offer few sustainable financial products. The purpose of the study is to explore the current gap between supply and demand of sustainable financial investments in German retail banking from a financial advisor’s point of view. We use qualitative analysis of interviews with financial advisors based on a Grounded Theory approach with the aim to identify the key causation in the cause-effect ...
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Welchen Herausforderungen begegnen Kreativdirektor/innen in Werbeagenturen? Exploration einer neuen Zielgruppe für Beratung
(2022-03-18)
Obwohl creative leadership zu den buzzwords der letzten Jahre gehörte, sind Kreativdirektor/innen in Werbeagenturen von der Wissenschaft in Deutschland bislang unbeachtet geblieben. Die vorliegende qualitative Untersuchung hat im Rahmen von sechs Interviews mit Kreativdirektor/innen analysiert, welchen Herausforderungen diese Zielgruppe in ihrem Berufsalltag begegnen. Das Ergebnis der Untersuchung zeigt, dass neben der Vereinbarung von kreativem Arbeiten mit Führungsaufgaben neue Organisationsformen, der digitale ...
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Protein Phosphatase Sit4 Affects Lipid Droplet Synthesis and Soraphen A Resistance Independent of Its Role in Regulating Elongator Dependent tRNA Modification
(2018-07-11)
The protein phosphatase Sit4 has been shown to be required for lipogenesis and resistance against the acetyl-CoA carboxylase inhibitor soraphen A. Since Sit4 is also required for biosynthesis of Elongator dependent tRNA modifications such as 5-methoxycarbonylmethyluridine (mcm5U), we investigated the relevance of tRNA modifications in lipogenesis and soraphen A response. While sit4 and Elongator (elp3) mutants copy defects in mcm5U formation and stress sensitivity, they do not share soraphen A sensitivity and low ...
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Weinen im Coaching – oder: Gehört der Taschentuchspender in jede Coachingpraxis?
(2022-03-30)
Das Weinen als fundamentaler menschlicher Emotionsausdruck wirft innerhalb verschiedener Fachdisziplinen seit jeher Fragen auf. In den letzten Jahren lässt sich auch innerhalb der klinischen Forschung eine zunehmende Beschäftigung mit diesem Thema beobachten. U. a. konnte im Rahmen einer Untersuchung an der Universität Kassel eine Systematisierung über verschiedene Formen des Weinens in der Psychotherapie und unterschiedliche therapeutische Verhaltensweisen im Umgang damit entwickelt werden. Im vorliegenden Artikel ...
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A Study on the Influence of the Chemical Nature of Fillers on Rheological and Fatigue Behavior of Bitumen Emulsion Mastic
(2020-10-16)
Cold Bitumen Emulsion (CBE) mixture technologies have been recently developed to lower pavement construction temperatures to reduce environmental costs and control gas emissions. Due to its poor early mechanical strength, active fillers (i.e., cement) have been used to obtain high early sti ness in order to have the potential for timely construction of the next layer. There is, however, a lack of understanding about the impact of active fillers on the viscoelastic behavior and fatigue damage resistance of CBE mastics. ...