The synthesis of glycerolipids starts with the acylation of lipid backbones. Two structurally different glycerolipids emerge in the cell: ether-lipids and ester-lipids. In the case of ether-lipids the first fatty acid is substituted with a fatty alcohol inside the peroxisome. By the characterization of the protein FARAT in this thesis, a key enzyme in etherlipid-synthesis was identified for D. discoideum. FARAT shows a peroxisomal localization and is in principle able to do two jobs. Firstly, it initiates the peroxisomal ...

In 2009, our group published two stable N-heterocyclic carbenes (NHCs) with a 1,1'-ferrocenediyl backbone (fc), which formally exhibit a six-membered FeIIC2N2CII-heterocycle. The stabilization of the fcNHCs is favored by bulky N-substituents. So far neopentyl and 2-adamantyl have been used for this purpose - a bulky primary and secondary alkyl substituent. In contrast to other cyclic diaminocarbenes, the fcNHCs are capable of activating small molecules such as NH3 or CO. The reason for this remarkable ability is the ...

The dissertation “Rethinking the genus Hyphodontia s.l. (Hymenochaetales, Basidiomycota) – investigations on a worldwide scope including new taxonomy, phylogeny, and identification keys” was elaborated by Janett Riebesehl in the Department of Ecology at the University of Kassel. Changing the classification system of the fungal genus Hyphodontia s.l. to treat the species from the broad Hyphodontia s.l. concept by a division into other genera was continued. Hjortstam and Ryvarden (2002, 2009) began the concept, but ...

A Laurent-Puiseux series $$ \sum\limits_{n = n_0}^{\infty }{a_n (z - z_0)^{n/k} (a_n \in K, k \in ℕ, n_0 \in ℤ ) } \quad (1) $$ where $ k $ denotes the corresponding Puiseux number and $ K $ an infinite computable field - mostly $ K= ℚ(α_1,\ldots,α_n) $ : a field of rational functions in several variables, is mainly characterized by the general coefficient. We consider the case where an is a term of an m-fold hypergeometric sequence. That is $ a_{n+m} = r(n) a_n $ for all sufficiently large integers $ n, r(n) $ ...

The expansion of long-distance data communication at a wavelength of 1.55 µm calls for larger data transfer rates. Consequently, an improvement of emission and modulation properties of lasers emitting in this wavelength region is of high interest. The utilization of so-called tunnel-injection (TI) structures in InP-based quantum dot (QD) lasers is promising to fulfill this task. The aim of this thesis was the realization and analysis of TI structures in the lattice matched InP material system and incorporation into ...

The thesis at hand investigates the suitability of quantum dot (QD) material for use in long-distance coherent communication. The thesis was written in the frame of the SASER project MONOLOP that is aiming for a compact, monolithically integrated light source with a tunable wavelength covering the C+-band and narrow spectral linewidth below 500 kHz. The thesis reviews the theoretical background of quantum dot material based on the InP material system and distributed feedback (DFB) lasers with lateral gratings as ...

Description of a research project, which tries to realize a VR-game for learning chemistry on the macroscopic and on the microscopic level.

Diamond is a material with excellent properties due to its structure and composition. Its crystal lattice is a perfect host of different defect centers, so-called color centers, whose properties, especially the capability of emitting single photons, can serve in quantum information technologies (QIT). As a high refractive index material only a small part of the photons emitted by these color centers in diamond can be collected. To enhance the photon collection efficiency photonic structures are necessary. They can ...

In dieser Arbeit sollten neue Interaktionspartner der regulatorischen Untereinheit (R-UE) der Proteinkinase A (PKA) und des Modellorganismus C. elegans identifiziert und funktionell charakterisiert werden. Im Gegensatz zu Säugern (vier Isoformen), exprimiert der Nematode nur eine PKA-R-Isoform. Mittels in silico Analysen und so genannten „Pulldown“ Experimenten, wurde insbesondere nach A Kinase Ankerproteinen (AKAP) in C. elegans gesucht. Aus in silico Recherchen resultiert das rgs5 Protein als mögliches Funktionshomolog ...

Die Erforschung der Biologie maligner Tumoren beschränkte sich über lange Zeit auf die Suche nach genetischen Veränderungen. Dies hat sich in den letzten Jahren grundlegend geändert, da sich aus dem Wissen um die molekularen Veränderungen in den frühesten histomorphologisch erkennbaren Vorläuferläsionen neue Möglichkeiten zur Früherkennung und Prävention maligner Tumoren ergeben. Darüber hinaus gewinnen Aspekte zur Aufklärung des Krebs- und Progressionsrisikos zunehmend an Bedeutung. Voraussetzung für die Beantwortung ...