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Binding of the Human 14-3-3 Isoforms to Distinct Sites in the Leucine-Rich Repeat Kinase 2
(2020-04-07)
Proteins of the 14-3-3 family are well known modulators of the leucine-rich repeat kinase 2 (LRRK2) regulating kinase activity, cellular localization, and ubiquitylation. Although binding between those proteins has been investigated, a comparative study of all human 14-3-3 isoforms interacting with LRRK2 is lacking so far. In a comprehensive approach, we quantitatively analyzed the interaction between the seven human 14-3-3 isoforms and LRRK2-derived peptides covering both, reported and putative 14-3-3 binding sites. ...
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3D Micro/Nanopatterning of a Vinylferrocene Copolymer
(2020-05-23)
In nanoimprint lithography (NIL), a pattern is created by mechanical deformation of an imprint resist via embossing with a stamp, where the adhesion behavior during the filling of the imprint stamp and its subsequent detachment may impose some practical challenges. Here we explored thermal and reverse NIL patterning of polyvinylferrocene and vinylferrocene-methyl methacrylate copolymers to prepare complex non-spherical objects and patterns. While neat polyvinylferrocene was found to be unsuitable for NIL, freshly-prepared ...
Aufsatz
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Entrepreneurial Coaching: A Two‐Dimensional Framework in Context
(2020-05-08)
Coaching is increasingly used to support entrepreneurs across different stages of the entrepreneurial process. Due to its custom‐tailored, active, and reflection‐oriented approach, it has been suggested that it is particularly well suited to entrepreneurs’ complex job demands. However, in the entrepreneurial context, the term coaching lacks a clear definition and is frequently used interchangeably with other types of support. We therefore sought to characterize entrepreneurial coaching (EC) and to position it relative ...
Aufsatz
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Fluorescence Microscopy of Superplasticizers in Cementitious Systems: Applications and Challenges
(2020-08-24)
In addition to the desired plasticizing effect, superplasticizers used in high and ultra-high performance concretes (UHPC) influence the chemical system of the pastes and for example retardation of the cement hydration occurs. Thus, superplasticizers have to be chosen wisely for every material composition and application. To investigate the essential adsorption of these polymers to particle surfaces in-situ to overcome several practical challenges of superplasticizer research, fluorescence microscopy is useful. In ...
Aufsatz
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Assessment of the N- and P-Fertilization Effect of Black Soldier Fly (Diptera: Stratiomyidae) By-Products on Maize
(2020-09-22)
To meet the growing demand for an alternative animal protein source, the Black Soldier Fly (BSF) (Hermetia illucens) industry is expanding. Thus, the valuation of its byproducts, foremost BSF frass, is getting more economic and ecological weight. Three different residues, BSF frass, larval skins, and dead adult flies, were compared with a mineral and an organic commercial fertilizer in a pot trial with maize (Zea mays L., [Poales: Poaceae]). byproducts were applied in three nutrient-based application rates (180; 215 ...
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Kötzing, Andreas (Hrsg.): Bilder der Allmacht. Die Staatssicherheit in Film und Fernsehen, 336 S., Wallstein, Göttingen 2018.
(2020-07-13)
Die DDR war nicht gerade ein Staat, der geeignet gewesen wäre, den Glamour Hollywoods anzuziehen. Der Stasi gelang in gewisser Weise allerdings auch dies: Der Mauerbau und die besondere Lage Berlins beflügelten schnell die Fantasien von Filmschaffenden und so entstanden gerade in den 1960er Jahren eine Reihe hochkarätig besetzter Filme, in denen sich etwa Paul Newman („Der zerrissene Vorhang“, 1966) oder Richard Burton („Der Spion, der aus der Kälte kam“, 1965) mit den Machenschaften der Stasi auseinandersetzen ...
Aufsatz
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Die Entwicklung und Anwendung konfliktspezifischer Geschichtenergänzungsaufgaben als Teil der OPD-Diagnostik im Kindesalter
(2020-02-24)
Die Studie verbindet die MacArthur Story Stem Battery (MSSB) mit der Operationalisierten Psychodynamischen Diagnostik im Kindes- und Jugendalter (OPD-KJ-2). Dargestellt wird die Entwicklung und Anwendung von konfliktspezifischen Geschichtenergänzungsaufgaben für eine systematische Einschätzung der Konflikt- und Strukturachse in der Altersgruppe 2 (6–12 Jahre). Für die Achsen Konflikt und Struktur wird die Interrater-Reliabilität bestimmt. Weiterhin werden explorativ Zusammenhänge zwischen der Konflikt- und Strukturachse ...
Aufsatz
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Homodinuclear Rhˡ and Irˡ Complexes Derived from Imidazolium-Benzimidazolates
(2020-11-19)
The reactions of [M(μ-Cl)(COD)]2 (M=Rh, Ir) with the conjugated mesomeric betaines 2-(3-methyl-1-imidazolium)-benzimidazolate (1aH), 2-(3-isopropyl-1-imidazolium)-benzimidazolate (1bH) and 2-(3-tert-butyl-1-imidazolium)-benzimidazolate (1cH) in equilibrium with their carbenic tautomers 1’aH, 1’bH and 1’cH were investigated. In the case of 1aH and 1bH, the homodinuclear complexes [MCl(COD){M(μ-1’a)(COD)}] and [MCl(COD){M(μ-1’b)(COD)}] were obtained, whose anionic NHC ligand 1’a− or 1’b− bridges the metal centres in a ...
Aufsatz
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Calculation of optical gain in AlGaN quantum wells for ultraviolet emission
(2020-09-03)
Stimulated emission from AlGaN based quantum wells (QWs) emitting at ultraviolet wavelengths is investigated theoretically. Maxwell–Bloch equations in the second Born approximation are solved self-consistently with the Poisson equation. The valence band dispersion is obtained from a 6-band kp-model. For a QW emitting at around 270 nm with a thickness of 2.2 nm, an estimated FWHM of 10 meV for homogeneous broadening and an excitonic red shift of 100 meV are extracted under typical laser conditions. From a comparison ...
Aufsatz
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Tensions in sustainable warehousing: including the blue-collar perspective on automation and ergonomic workplace design
(2020-05-14)
In many industrial countries, demographic changes towards an aging society go hand in hand with the need for ergonomic workplaces. Therefore, it is necessary to rethink workplace designs and work processes, particularly in industrial professions, such as logistics. As logistics activities are still characterized by a high amount of manual effort, they represent a suitable field for gaining empirical insights into the implementation of automation and ergonomic practices to inform social sustainable warehousing logistics ...